Size  100ug
Cat code  200350-D6
Species Cross-reactivity  H
Key Application  WB
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG2a
Molecular Weight  96kDa
Sensitivity  This antibody detects endogenous levels of ICAM1(C-term.) and does not cross-react with related proteins.
Immunogen  Purified recombinant human ICAM1(C-term.) protein fragments expressed in E.coli.
UniProt Number  P05362
GeneBank ID  NM_000201
Subcellular location  Membrane; Single-pass type I membrane protein.
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  ICAM-1,human rhinovirus receptor,cell surface glycoprotein P3.58 major group rhinovirus receptor,intercellular adhesion molecule 1 (CD54), human rhinovirus receptor;ICAM1;
Gene_symbol  BB2; CD54; P3.58
Summary  This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
UniPort summary  Function  ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Application Images :  
Western blot detection of ICAM1 in Raji&SW480 cell lysates and  using ICAM1 antibody (1:1000 diluted). 
Predicted band size: 58KDa 
Observed band size: 96KDa