Size  100ug
Cat code  200504
Species Cross-reactivity  H
Key Application  WB
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG2a
Molecular Weight  70kDa
Sensitivity  This antibody detects endogenous levels FOXO1(C-terminus) and does not cross-react with related proteins.
Immunogen  Purified recombinant human FOXO1(C-terminus) protein fragments expressed in E.coli.
UniProt Number  Q12778
GeneBank ID  NM_002015
Subcellular location  Cytoplasm. Nucleus
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  FKH1; FKHR; FOXO1A
Gene_symbol  FKH1; FKHR; FOXO1A
Summary  This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead
domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth
and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
UniPort summary  Function  Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence (By similarity)
Application Images :  
Western blot detection of FOXO1(C-terminus) antibody in A431&Hela cell lysates using FOXO1(C-terminus) antibody (1:1000 diluted).
Predicted band size:70KDa
Observed band size: 70KDa.