Size  100ug
Cat code  200607
Species Cross-reactivity  H,M
Key Application  WB
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG1
Molecular Weight  45kDa
Sensitivity  This antibody detects endogenous levels of JUN and does not cross-react with related proteins.
Immunogen  Purified recombinant human JUN protein fragments expressed in E.coli.
UniProt Number  P05412
GeneBank ID  NM_002228
Subcellular location  Nucleus.
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
Altername  jun oncogene,activator protein 1,proto-oncogene c-Jun,enhancer-binding protein AP1,Jun activation domain binding protein,v-jun sarcoma virus 17 oncogene homolog,v-jun avian sarcoma virus 17 oncogene homolog
Gene_symbol  AP1; AP-1; c-Jun
Summary  This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
UniPort summary  Function  Transcription factor that recognizes and binds to the enhancer heptamer motif 5´-TGA[CG]TCA-3´. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Application Images :  
Western blot detection of JUN  in :293 &3T3 cell lysates(1:1000 diluted).  
Predicted band size: 36KDa       
Observed band size: 45KDa.