Size  100ug
Cat code  200780
Species Cross-reactivity  H
Key Application  WB,ICC
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG2b
Molecular Weight  76kDa
Sensitivity  This antibody detects endogenous levels of ALPP and does not cross-react with related proteins.
Immunogen  Purified recombinant human ALPP protein fragments expressed in E.coli.
UniProt Number  P05187
GeneBank ID  NM_001632
Subcellular location  Cell membrane; Lipid-anchor ? GPI-anchor
Formulation  Purified mouse monoclonal in PBS(pH 7.4) containing  with 0.2% sodium azide, 50% glycerol, 0.1%BSA
Altername  Alkaline phosphatase Regan isozyme;Placental alkaline phosphatase 1
Gene_symbol  ALP; PALP; PLAP; PLAP-1
Summary  There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3´ untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
UniPort summary  Function  null
Application Images :  
Western blot detection of ALPP in Hela,LNCap,human Placenta &A549 cell lysates and  using ALPP antibody (1:500 diluted). Predicted band size: 76KDa Observed band size:76KDa
Immunocytochemistry stain of Hela using ALPP antibody (1:300).