Size  100ug
Cat code  200423
Species Cross-reactivity  H,M
Key Application  WB
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG2a
Molecular Weight  37kDa
Sensitivity  This antibody detects endogenous levels of PPP1CB and does not cross-react with related proteins.
Immunogen  Purified recombinant human PPP1CB protein fragments expressed in E.coli.
UniProt Number  P62140
GeneBank ID  NM_206876.1
Subcellular location  Cytoplasm. Nucleus
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  protein phosphatase 1, catalytic subunit, beta isozyme;PP-1B;PP1beta;protein phosphatase 1-beta;PPP1CD
Gene_symbol  PP-1B; PPP1CD; PP1beta 
Summary  The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
UniPort summary  Function  Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. 
Application Images :  
Western blot detection of PPP1CB in Mouse brain,F9&MCF7 cell lysates using PPP1CB antibody (1:1000 diluted).
Predicted band size:37KDa.
Observed band size:37KDa